Dr. David Minkoff MS

Search for Perfect Proteins

Aired on: May 14, 2022

Episode Description

Proteins are the basic building blocks of the human body. But most people are malnourished in amino acids, which are required to form protein—a deficiency that can lead to diabetes, obesity, cancer, and chronic diseases. It’s a serious problem for which Dr. David Minkoff offers a powerful solution in The Search for the Perfect Protein. A medical doctor and Ironman triathlete, Dr. Minkoff provides a new appreciation and understanding of these vital components of life and wellness. He examines the healthful or harmful effects of the foods you eat regularly. And he explores the importance of clean proteins in your diet while offering indispensable guidance on where to find them. Not all proteins are created equal, and they’re not just for bodybuilders. Whether you’re female or male, young or old, an athlete or couch potato, The Search for the Perfect Protein will lead you to a stronger, healthier life

Dr. David Minkoff MS


Lifeworkswellnesscenter.com for chronic diseases

His history

  • He did a lot of athlete training and pulled his hamstring
  • He could not heal it solidly, he tried everything to rehab the muscle
  • He found that mixtures of amino acids helped his hamstring repair
  • Eating food, the body has to break them down to individual amino acids, and then the body reassembles them
  • He experimented with the eight essential amino acids.
    • These eight amino acids are always in amino acid mixtures
  • He tested many people and found they were amino acid deficient
  • When he supplemented with these eight amino acids, people improved

The structure of the body including neurotransmitters, bone, enzymes, receptors, muscles are all made out of amino acids

  • Amino acids are found in 100,000s different proteins
    • detox pathways, krebs cycle, liver systems, immune system, antibodies
  • There are 22 amino acids
  • There are 8 essential amino acids
    • With these amino acids, we can heal
  • The body is continually trying to replace these amino acids which are damaged by exercise and chemical injuries
  • Cells have to remake these so need amino acids to replace these
  • There is no storage of amino acids, so if there are not enough amino acid, the protein won’t be made
    • If someone is sore after exercise, it means the proteins did not repair
    • Some have problems with digestion of amino acids
      • If one takes stomach acid blockers then they won’t digest protein
      • 25 million prescriptions are written monthly for ant acids plus these medications are over the counter
      • Need stomach acids to digest proteins.  Undigested proteins in the blood stream can lead to autoimmune diseases

Symptoms of protein malnourishment

  • Hair falling out, brittle nails, low energy, depression, anxiety, trouble sleeping, depression, painful periods, thyroid difficulties, depend on amino acids
    • Symptoms can be traced back to a lack of a enzyme protein
    • Hair and nails grow slower
  • Half of his patients have chronic conditions, cancer, multiple sclerosis, lyme disease, Parkinson’s, chronic fatigue, dementia – all have amino acids deficiency
  • He sees amino acid deficiencies in athletes
  • Low amino acid levels, à low pancreatic digestive enzymes
  • With poor food quality, toxins, persons with poor gut, low digestive enzymes,
  • Amino acids are needed for high turnover tissues such as the
    • gut tissue which breaks down
      • if can’t digest can lead to diarrhea, constipation and more nutritional deficiencies
    • Blood cells
    • Hair
    • Wounds
    • Bone
  • Without the essential amino acids, these tissues will replace slower

Look for fasting levels of amino acids

  • Can measure levels of chymotrypsin, protein digesting enzyme in pancreas, most have low levels so they won’t digest proteins
  • He measures Genova amino acids levels and nutrient deficiencies

Causes amino acid deficiencies

  • Diet
    • A good part of gatherers for our ancestors were hunter gatherers
    • All vegetarians and vegans are low in amino acids
      • Their diets are low in plant protein
    • There are essential fats, vitamins and amino acids that they body needs
      • In the past, the food was better, the toxins were fewer, and food might have been sufficient
      • Getting the right foods and digesting them is reason for chronic disease. – people are malnourished. 
      • In 1900 heart disease, diabetes, osteoporosis were rare
      • The age of optimal health is 27
  • Abnormal gut so can’t absorb
    • Leaky gut inadequate membrane
      • Damage to gut membrane which is made out of proteins
      • Roundup, glyphosate, chemicals in pesticides, almost all drugs, mercury in fish
      • Have to heal gut

Causes of leaky gut

  • Low stomach acids
  • Antibiotics
  • Gluten
  • All pharmaceuticals
  • Alcohol
  • Nightshades
  • Stress

Symptoms of leaky gut

  • Bloating, heart burn, constipation, diarrhea
  • Undigested proteins which cross the membrane, and body makes antibodies, an attack protein
    • Molecular mimicry so immune system starts attacking body
      • Joint pain, brain fog, skin rashes, liver enzyme elevation
  • Get bad bacteria or the cell wall of the bad bacteria (LPS) crossing into the system
    • These are inflammatory
    •  can go to muscles, heart arteries (causing heart attacks), joints
  • Eg gluten has molecular mimicrky goes after purkinje cells (balance cells) in cerebellum, goes aft eyelet cells (resulting in autoimmune diabetes) or thyroid

Need amino acids every few days to regenerate gut

Causes protein malnourishment

  • Any stress
  • Medications
  • Chemical stress
  • Toxins causing cellular injuries
  • Environmental pollution
  • Chemicals
  • Heavy metals
  • Food
  • Pesticides
  • EMF

Do high protein diets solve protein malnourishment?

  • Need to be able to digest and absorb protein to provide a low of amino acids coming in
  • Difficult for vegetarians need to get proteins, and be able to digest and absorb it
  • Some bodies need more
    • Eg a lot of exercise

Need ratio of amino acid ?

  • Categories of food fats, carbohydrates and amino acids
  • Amino acids are made into proteins
  • All three categories are made of carbon, hydrogen and oxygen
  • Amino acids have nitrogen
  • Whey protein 16 % protein
    • If all the protein from whey were used to make protein, these proteins would be urinated out of the body
    • Pees out excess nitrogen (urea)
    • Only about 16 % of proteins in whey are used in the body
    • Whey is a poor protein
      • Meat is double the percentage used (32 %)
      • Eggs are triple that  (48 %)
    • Plant, rice, bean, pea protein are poor suppliers of amino acids
    • Collagen is worst as is missing tryptophan one of 8 amino acids
      • Body cannot make protein out of collagen


  • If proteins and amino acids are not sufficient, calcium will not help
  • Are 50 % protein: are collagen
  • If collagen is there, then mineral calcium and phosphorous would stick to it
  • Calcium alone will not build bones if amino acid deficient
  • Give amino acids with the right kind of exercise, would help
  • The mineral acids would be put into collagen, then minerals (calcium and phosphorous) will be placed into bone
  • Also needed magnesium,
  • vitamins C, K2, B 6
  • balanced hormones such as thyroid, estrogen, progesterone, DHEA, testosterone
  • is fine orchestra so is better to get from whole food

Saggy Skin

  • skin is protein so sags without protein


  • lack of serotonin and maybe GABA
  • is made out of tryptophan which is needed for serotonin
  • SSRIs don’t fix the problem which is nutrition problem; they poison the nerves which last for a while
  • Need to fix the gut as most of serotonin is made in the gut with the right gut bacteria
  • Need to fix gut bacteria
  • Need to fix the malnutrition (tryptophan, perfect aminos)
  • Give 10 day antibiotics, 20 % patients will feel depressed because of the wreckage on gut bacteria
  • If have a double round of antibiotics, 40 % patient will be depressed
  • Also need magnesium, vitamin B 6, stomach acid
    • Acid blockers can interfere

Weight gain

  • Some is toxins inflammation, some over consumption of wrong foods
  • He found if people substituted their proteins with perfect aminos (2 scoops is a better protein will reduce calories but will still be well nourished.

Percentages of proteins utilized from other sources

  • Breast milk. 49 %
  • Whole Eggs 48 % (methionine is in the yolk is the most perfect protein except breast


  • Meat, fish fowl 48 %
  • Soy. 17.5
  • Dairy 16 – 84  %
  • Egg white 17 %
  • Spirulina. 6 %
  • Whey protein 16 % poor supplier  
  • Soy  16 %   and has problems with estrogen, GMO


  • Ten grams of amino acids per day
  • Plant, rice, bean, protein, pea proteins are poor suppliers
  • Collagen does not convert to proteins because it does not contain tryptophan

He recommends perfect amino

  • It is predigested
  • If take on an empty stomach will be in blood stream in 23 minutes
    • These amino acids will go to cells so cells can make what is needed
  • Does not interact with other medications

Excess amino acids are peed out